2-Amino-5-Nitrothiazole | CAS No.: 121-66-4

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 Chemical Name: 2-Amino-5-Nitrothiazole

CAS No.: 121-66-4

Molecular Formula: C3H3N3O2S

Molecular Weight: 145.14 g/mol

Appearance: Yellow to orange crystalline powder

Solubility: Slightly soluble in water, soluble in ethanol, methanol, and organic solvents

Storage Conditions: Store in a cool, dry, and well-ventilated place, avoiding direct sunlight and moisture.

What is 2-Amino-5-Nitrothiazole?

2-Amino-5-Nitrothiazole is a heterocyclic compound containing both amino and nitro functional groups, making it highly reactive in organic synthesis. It is widely used as an intermediate in pharmaceuticals, veterinary medicine, and dye production due to its strong antimicrobial properties.

Functions and Applications of 2-Amino-5-Nitrothiazole

Pharmaceutical Industry

Used as an intermediate in the synthesis of antibacterial and antiparasitic drugs.

It has been historically studied for its antimicrobial properties and potential applications in treating bacterial and protozoal infections.

Veterinary Medicine

Commonly incorporated into veterinary formulations to combat infections in livestock and pets.

Used in the production of drugs targeting gastrointestinal infections caused by protozoa.

Chemical and Industrial Applications

Functions as an intermediate in the synthesis of dyes, pigments, and agrochemicals.

Utilized in the development of specialty chemicals requiring a nitrothiazole scaffold.

Safety and Side Effects

May cause skin, eye, and respiratory irritation; protective gloves, masks, and goggles should be worn when handling.

Some nitrothiazole derivatives have been associated with toxicity concerns; proper handling and disposal procedures must be followed.

Prolonged exposure or ingestion may pose health risks and should be avoided.

Conclusion

1-Amino-5-Nitrothiazole is a versatile heterocyclic compound widely used in pharmaceutical, veterinary, and industrial applications. Its strong antimicrobial properties make it valuable in drug synthesis, while its nitrothiazole structure allows for diverse chemical applications. Proper precautions should be taken to ensure safe handling and minimize potential health risks.