4-Hydroxyphenazone | CAS No.: 2420-17-9

��发布时间：2025-02-28 ��浏览次数：794次

Chemical Name: 4-Hydroxyphenazone

CAS No.: 2420-17-9

Molecular Formula: C11H12N2O2

Molecular Weight: 204.23 g/mol

Appearance: White to off-white crystalline powder

Solubility: Soluble in ethanol, methanol, and DMSO; slightly soluble in water

Storage Conditions: Store in a cool, dry, and light-protected environment, avoiding high temperatures and humidity.

What is 4-Hydroxyphenazone?

4-Hydroxyphenazone is a pyrazolone-derived compound with anti-inflammatory, antipyretic, and analgesic properties. It serves as an active ingredient in certain non-steroidal anti-inflammatory drugs (NSAIDs) or pain relievers and is commonly used in the preparation of pharmaceutical intermediates or medical research.

Functions and Applications of 4-Hydroxyphenazone

Pharmaceutical Industry

This compound belongs to the pyrazolone class of antipyretic and analgesic drugs, capable of reducing fever and alleviating mild to moderate pain.

As an intermediate in drug synthesis, it is used for developing other antipyretic and analgesic medications or anti-inflammatory drugs.

Chemical Research

In medicinal chemistry and organic synthesis, 4-Hydroxyphenazone is commonly used as a structural modification unit to optimize the biological activity and pharmacokinetic properties of drugs.

Due to its pyrazolone scaffold, it can also be used to synthesize novel anti-inflammatory or antioxidant molecules.

Other Applications

This compound may be studied for its potential use as an antioxidant or stabilizer in the food or cosmetic industries.

It may also be applied in analytical chemistry for specific detection methods.

Safety and Side Effects

This compound may cause mild irritation to the skin, eyes, and respiratory tract; protective gloves and goggles should be worn during handling.

Prolonged or high-dose exposure may place a burden on the liver or kidneys and should be used under medical supervision.

Some individuals may experience allergic reactions such as rashes or respiratory irritation; direct contact should be avoided.

Conclusion

4-Hydroxyphenazone is a pyrazolone-based compound widely used in the pharmaceutical industry, primarily as an active ingredient or intermediate in antipyretic and analgesic drugs. Additionally, it has applications in drug synthesis and organic chemistry research. Proper handling precautions should be taken to minimize potential side effects associated with prolonged or high-dose exposure.