Ivermectin 70288-86-7

��发布时间：2025-03-27 ��浏览次数：1158次

 Chemical Name: Ivermectin

CAS Number: 70288-86-7

Molecular Formula: C48H74O14

Molecular Weight: 875.1 g/mol

Appearance: White to pale yellow crystalline powder

Solubility: Soluble in organic solvents such as ethanol, slightly soluble in water

Storage Conditions: Store in a cool, dry place, protected from light and high temperatures.

What is Ivermectin?
Ivermectin is a broad-spectrum antiparasitic agent initially used to treat parasitic infections in animals. It is derived from Streptomyces avermitilis, a soil bacterium. Ivermectin has been widely used to treat parasitic infections in both humans and animals and is considered a highly effective medication.

Mechanisms and Applications of Ivermectin

Treatment of Parasitic Infections
The most common use of Ivermectin is to treat infections caused by parasites. For example, it is widely used to treat nematode infections (such as river blindness and lymphatic filariasis), helminth infections (such as whipworm and roundworm), and skin conditions like head lice and scabies.

Treatment of Skin Diseases
Ivermectin plays a significant role in treating parasitic skin diseases, such as scabies. It works by inhibiting the nervous system of the parasites, leading to their death and alleviating symptoms. It is also used to treat infections caused by head lice and body lice.

Treatment of River Blindness (Onchocerciasis)
Ivermectin is crucial in treating river blindness caused by Onchocerca volvulus. It kills the microfilariae of the parasite, slowing or stopping its transmission, and helps improve patients' vision and quality of life.

Treatment of Lymphatic Filariasis
Ivermectin is also highly effective in treating lymphatic filariasis (such as elephantiasis) caused by Wuchereria bancrofti. It reduces the number of parasites in the body, alleviates symptoms, and prevents further transmission of the disease.

New Applications: Antiviral Effects
In recent years, Ivermectin has been studied for its antiviral potential, particularly in research on COVID-19 treatments. Although it has shown some antiviral potential in laboratory studies, its clinical use is still under further evaluation.

Veterinary Medicine
As an animal medication, Ivermectin is widely used in veterinary medicine, particularly for treating parasitic infections in livestock and pets. It effectively treats various internal and external parasites, including nematodes, fleas, and helminths.

Safety and Side Effects
Ivermectin is generally considered safe when used as directed. However, professional guidance should be followed. Common side effects include headache, dizziness, nausea, and gastrointestinal discomfort, especially at high doses. Caution is advised for individuals with low body weight or weakened immune systems.

Summary
Ivermectin is a broad-spectrum antiparasitic drug widely used to treat various parasitic infections in humans and animals. It has shown significant efficacy in treating parasitic skin diseases, river blindness, and lymphatic filariasis. While its clinical applications are well-established, recent antiviral research has opened new therapeutic possibilities for this medication.