Tetramisole Hydrochloride CAS 5086-74-8

��发布时间：2025-03-27 ��浏览次数：914次

 Chemical Name: Tetramisole Hydrochloride

CAS Number: 5086-74-8

Molecular Formula: C9H12ClN3S

Molecular Weight: 227.73 g/mol

Appearance: White to off-white crystalline powder

Solubility: Soluble in water, ethanol, and methanol

Introduction:

Tetramisole hydrochloride is a widely used anti-parasitic drug in veterinary medicine. Initially used as an anthelmintic for livestock, particularly effective against worm infections (such as nematodes), Tetramisole has also been used in humans for treating certain parasitic diseases, though it has been largely replaced by more modern drugs in many countries.

Tetramisole has gained attention for its immunomodulatory properties, as some studies suggest it can enhance immune responses by stimulating the immune system. It works by inhibiting the neuromuscular system of parasites, leading to their paralysis and expulsion.

Actions:

Anti-Parasitic Effects: Tetramisole hydrochloride was initially used as an anti-parasitic drug, especially effective in treating nematode infections (such as roundworms and whipworms). It works by inhibiting nerve transmission in parasites, causing paralysis and expulsion.

Immunomodulatory Effects: Recent studies have found that Tetramisole hydrochloride can have effects on the immune system. It can stimulate certain immune cells (such as T cells and B cells), thereby enhancing the body’s immune response. This characteristic has made Tetramisole a potential candidate in research for immune-related diseases.

Cancer Potential: Preliminary studies suggest that Tetramisole may have anti-cancer potential. By enhancing immune system function, it may help fight tumor cells, although research in this area is still ongoing.

Opioid Dependence Treatment: Tetramisole has also been studied as an adjunct for opioid dependence treatment, particularly in alleviating withdrawal symptoms and suppressing addiction, though this use has not been widely adopted.

Applications:

Veterinary Medicine: Tetramisole hydrochloride is used as an anti-parasitic in animal husbandry, especially effective in treating worm infections in livestock.

Immunomodulation: In some immunological studies, Tetramisole is used as an immune enhancer to explore its applications in immune system disorders.

Clinical Research: Some studies have investigated Tetramisole's potential in cancer immunotherapy, using it as an immune enhancer to improve the immune response to tumors.

Summary:

Tetramisole hydrochloride is an anti-parasitic drug originally used to treat nematode infections. With increasing research on its immunomodulatory effects, it has shown potential in immune enhancement and possibly in cancer treatment. Although primarily used in veterinary medicine, Tetramisole’s immune-modulating properties make it an interesting candidate in certain research fields.