Tranexamic Acid 1197-18-8

��发布时间：2025-03-27 ��浏览次数：285次

 Chemical Name: Tranexamic Acid

CAS Number: 1197-18-8

Molecular Formula: C8H15NO2

Molecular Weight: 157.21 g/mol

Appearance: White crystalline or crystalline powder

Solubility: Easily soluble in water

Storage Conditions: Store in a cool, dry place, away from direct sunlight

What is Tranexamic Acid?
Tranexamic Acid is a synthetic derivative of an amino acid, widely used in the treatment of various conditions caused by excessive bleeding. It works by inhibiting the activity of plasminogen, thus reducing fibrinolysis and promoting blood clotting. Unlike other hemostatic agents, Tranexamic Acid helps blood coagulate by reducing plasmin activity in the bloodstream. In addition to its clinical use for hemostasis, Tranexamic Acid is also widely used in cosmetic products, especially in the treatment of skin pigmentation disorders.

Tranexamic Acid Functions and Applications

Clinical Hemostasis

Tranexamic Acid is most commonly used as a hemostatic agent, especially in controlling excessive bleeding after surgeries or trauma. It works by inhibiting plasminogen activation, reducing fibrinolysis, and helping form blood clots, effectively preventing and treating bleeding.

Treatment of Menorrhagia (Heavy Menstrual Bleeding)

Tranexamic Acid is also widely used in gynecology, particularly for treating menorrhagia (heavy menstrual bleeding). It reduces the vascular permeability of the uterine lining, lowering the blood flow during menstruation and relieving discomfort caused by excessive bleeding.

Cosmetics and Skin Care

In the cosmetic field, Tranexamic Acid is used to reduce and treat pigmentation, such as freckles, melasma, and age spots. By inhibiting the activity of tyrosinase, it effectively reduces the production of melanin, helping improve uneven skin tone and pigmentation issues. Due to its anti-inflammatory and anti-pigmentation effects, Tranexamic Acid is increasingly being used in whitening and anti-aging products.

Prevention and Treatment of Thrombosis

In certain cases, Tranexamic Acid can be used to prevent thrombosis, particularly in high-risk patients. By reducing plasminogen activity in the blood, Tranexamic Acid helps prevent excessive blood clot dissolution, thus stabilizing the blood clotting process.

Topical Hemostasis and Wound Healing

Tranexamic Acid can also be used topically to manage localized wound bleeding, such as post-trauma bleeding. By locally reducing plasminogen activity, it aids in accelerating wound healing and reducing bleeding.

Safety and Side Effects
Tranexamic Acid is generally considered safe, especially for short-term use. Common side effects include nausea, vomiting, and abdominal pain, which usually disappear after discontinuation. Some patients may experience headaches, dizziness, or allergic reactions during use. Long-term or high-dose use may increase the risk of thrombosis, so it is not recommended for patients with a history of thrombosis or those using anticoagulants. Dosage should be adjusted according to medical advice to ensure safety.

Conclusion
Tranexamic Acid is a hemostatic agent used to effectively treat various conditions of excessive bleeding, such as surgery, trauma, and menorrhagia. In the cosmetic industry, it is widely used in whitening products due to its anti-pigmentation effects. Additionally, Tranexamic Acid has applications in controlling thrombosis and promoting wound healing. Overall, Tranexamic Acid is a versatile drug, but individual differences should be considered, and it should be used under medical guidance to avoid potential side effects.