Melanotan II MTII 121062-08-6

��发布时间：2025-03-27 ��浏览次数：569次

 Chemical Name: Melanotan II (MTII)

CAS Number: 121062-08-6

Molecular Formula: C50H69N15O9

Molecular Weight: 1024.18 g/mol

Structural Type: Cyclic Heptapeptide

Appearance: White or off-white powder

Solubility: Soluble in water and saline solution

Storage Conditions: Store at -20°C, protected from light, and keep dry

 

What is Melanotan II (MTII)?
Melanotan II (MTII) is a synthetic α-melanocyte-stimulating hormone (α-MSH) analog developed by scientists at the University of Arizona. It is designed to stimulate melanin production and reduce UV-induced skin damage. MTII enhances melanin production by acting on melanocortin-1 receptors (MC1R) on melanocytes, deepening skin pigmentation and mimicking a natural tanning effect without prolonged sun exposure.
In addition, Melanotan II can also affect other melanocortin receptors (MC3R, MC4R), which may influence sexual function, appetite, and metabolism, in addition to its skin pigmentation effects.

 

Functions of Melanotan II (MTII)

Promoting Skin Darkening (Tanning Effect)

MTII activates melanocortin-1 receptors (MC1R), stimulating melanin synthesis and darkening the skin, achieving a tan without prolonged sun exposure.

Advantages: Reduces UV exposure time, thereby lowering the risk of sunburn, skin aging, and skin cancer.

Applications: Commonly used by individuals seeking an even tan, such as bodybuilders and professionals in the beauty industry.

Impact on Sexual Function (Arousal Enhancement)

MTII can also activate melanocortin-4 receptors (MC4R), which are associated with erectile function and increased libido.

Studies show that MTII can be used to treat erectile dysfunction (ED) with effects similar to PDE5 inhibitors (e.g., sildenafil/Viagra), though the mechanisms differ.

Regulation of Appetite and Metabolism

By acting on melanocortin receptors 3 and 4 (MC3R and MC4R), MTII may suppress appetite and promote fat metabolism, making it considered by some to have potential weight loss effects.

Research shows that Melanotan II can reduce hunger and promote caloric expenditure, but its weight loss effects are still under study.

 

Potential Side Effects of Melanotan II (MTII)
While MTII shows potential benefits in tanning, beauty enhancement, and sexual function, it also has some side effects, including:

Nausea and vomiting (the most common side effect)

Facial flushing

Decreased appetite

Fatigue

Occasional high blood pressure

Darkening of moles (some users may notice their pre-existing moles darkening after use)

 

Conclusion
Melanotan II (MTII) is a synthetic melanocortin analog that promotes melanin production, achieving a tanning effect while potentially enhancing sexual function, suppressing appetite, and boosting metabolism. It is primarily used in the beauty, bodybuilding, and erectile dysfunction research fields. However, MTII has some potential side effects and should be used with caution, evaluating the risks before use.