Chrysophanol 481-74-3

��发布时间：2025-03-04 ��浏览次数：313次

 Chemical Name: Chrysophanol

CAS Number: 481-74-3

Molecular Formula: C15H10O5

Molecular Weight: 270.24 g/mol

Appearance: Yellow crystalline powder

Solubility: Slightly soluble in water, easily soluble in ethanol, ether, and other organic solvents

Storage Conditions: Store in a cool, dry place, avoiding light and moisture.

What is Chrysophanol?

Chrysophanol is a naturally occurring plant compound belonging to the anthraquinone family. It is widely found in plants such as Rheum species (rhubarb) and exhibits various pharmacological activities. Chrysophanol has attracted attention for its anti-inflammatory, antioxidant, antibacterial, and anticancer properties, making it a subject of interest in medical research.

Functions and Applications of Chrysophanol

1. Anti-Inflammatory Effects

Chrysophanol has significant anti-inflammatory properties and can inhibit the production of pro-inflammatory molecules, thereby reducing inflammation. It has shown therapeutic potential, particularly in diseases related to chronic inflammation.

2. Antioxidant Properties

As a potent antioxidant, Chrysophanol scavenges free radicals and reduces oxidative damage to cells. This protective effect helps prevent oxidative stress-related cell and tissue damage, making it a potential candidate for anti-aging and age-related disease prevention.

3. Antibacterial Activity

Chrysophanol exhibits antibacterial properties and can inhibit the growth of various bacteria, including common pathogenic strains. It is often used as a natural antibacterial agent, especially in traditional herbal medicine.

4. Anticancer Potential

Studies suggest that Chrysophanol may have anticancer properties by inhibiting cancer cell proliferation and inducing apoptosis (programmed cell death) in cancer cells. This makes it a promising candidate for anticancer research.

5. Liver Protection

Chrysophanol has been found to have hepatoprotective effects by modulating antioxidant enzyme activity in the liver, reducing liver damage. It may play a beneficial role in the supportive treatment of liver diseases.

6. Digestive Health Improvement

In traditional herbal medicine, Chrysophanol is used to improve digestion and promote intestinal motility. It has mild laxative effects, making it useful as a natural aid for constipation relief.

Safety and Side Effects

While Chrysophanol has demonstrated significant pharmacological benefits, its toxicity and side effects should not be overlooked. High doses may cause gastrointestinal discomfort, diarrhea, or other adverse reactions. Long-term or high-dose use should be approached with caution, and it is recommended to consult a healthcare professional before use.

Conclusion

Chrysophanol is a natural compound with multiple pharmacological activities, widely found in rhubarb and other plants. Its anti-inflammatory, antioxidant, antibacterial, anticancer, and hepatoprotective effects make it a valuable compound in both traditional herbal medicine and modern pharmacological research. However, proper dosage control is essential to minimize potential side effects.