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Nicotinamide Riboside Chloride (NR-Cl)

发布时间:2025-03-04 浏览次数:599次

Nicotinamide Riboside Chloride (NR-Cl)


 Chemical Name: Nicotinamide Riboside Chloride

CAS Number: 23111-00-4

Molecular Formula: C11H15N2O5Cl

Molecular Weight: 290.71 g/mol

Appearance: White or off-white crystalline powder

Solubility: Soluble in water and ethanol

Storage Conditions: Store in a cool, dry place, avoid moisture, and keep sealed.

 

What is Nicotinamide Riboside Chloride (NR-Cl)?

Nicotinamide Riboside Chloride (NR-Cl) is a derivative of nicotinamide and a naturally occurring precursor of NAD+ (Nicotinamide Adenine Dinucleotide). NAD+ plays a crucial role in various physiological processes, including energy metabolism, DNA repair, and cellular aging. As an effective NAD+ booster, NR-Cl has gained attention for its ability to enhance NAD+ levels in the body.

 

Functions and Applications of Nicotinamide Riboside Chloride

1. Increasing NAD+ Levels

NR-Cl effectively raises NAD+ levels in the body. NAD+ is a key molecule for maintaining cellular energy metabolism and supporting overall cellular function. Supplementing with NR-Cl enhances energy production and metabolic function, which can be particularly beneficial in aging or metabolic disorders.

2. Anti-Aging Benefits

Studies suggest that NR-Cl can activate various anti-aging mechanisms by increasing NAD+ levels. It stimulates the Sirtuin family of enzymes, which play vital roles in DNA repair, cellular health, and aging regulation. As a result, NR-Cl is considered a promising anti-aging supplement that may help slow down age-related cellular decline.

3. Supporting Energy Metabolism and Athletic Performance

Due to its ability to boost NAD+ levels, NR-Cl improves cellular energy metabolism and may enhance physical performance. Particularly after intense exercise or long-term training, NR-Cl supplementation may aid in recovery, boost endurance, and reduce fatigue.

4. Promoting Cardiovascular Health

Research indicates that NR-Cl supports cardiovascular health by increasing NAD+ levels. Since NAD+ is involved in vascular health, heart function, and blood pressure regulation, NR-Cl may help protect the cardiovascular system and reduce the risk of heart-related diseases.

5. Enhancing DNA Repair and Cellular Recovery

NAD+ is an essential cofactor in DNA repair processes, and increasing its levels through NR-Cl supplementation enhances cellular repair capabilities. Long-term use of NR-Cl may help reduce DNA damage and maintain cellular health, especially under oxidative stress or radiation exposure.

 

Safety and Side Effects

Nicotinamide Riboside Chloride is considered safe and generally has no significant side effects. Current studies suggest that long-term use at recommended dosages does not cause severe adverse reactions. However, some individuals may experience mild discomfort, such as gastrointestinal issues or skin reactions. It is advisable to follow dosage recommendations and adjust intake based on personal health conditions.

 

Conclusion

Nicotinamide Riboside Chloride (NR-Cl) is an effective NAD+ precursor that significantly increases NAD+ levels, supporting cellular metabolism, anti-aging, and overall health. Its key benefits include enhancing energy metabolism, improving athletic performance, promoting cardiovascular health, and facilitating DNA repair. As a widely researched and promising supplement, NR-Cl continues to gain attention in the fields of longevity and health optimization.

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