Urolithin A 1143-70-0

��发布时间：2025-03-03 ��浏览次数：1049次

 Chemical Name: Urolithin A

CAS Number: 1143-70-0

Molecular Formula: C13H8O4

Molecular Weight: 228.20 g/mol

Appearance: White to pale yellow crystalline powder

Solubility: Soluble in ethanol and dimethyl sulfoxide (DMSO), slightly soluble in water

Storage Conditions: Should be stored in a cool, dry place, away from direct sunlight

What is Urolithin A?

Urolithin A is a naturally occurring compound produced by the metabolism of certain food components, such as ellagic acid in pomegranates, by gut bacteria. It is a member of the urolithin family of compounds, and research has shown that it possesses multiple health benefits, including anti-inflammatory, antioxidant, and anti-aging properties. Urolithin A is closely linked to cellular health, mitochondrial function, and the delay of aging processes, particularly in promoting anti-aging and metabolic health.

Functions and Applications of Urolithin A

Promoting Mitochondrial Function
Urolithin A has been shown to significantly promote mitochondrial autophagy, the process by which damaged mitochondria are removed, helping to maintain cellular energy supply. As mitochondrial function tends to decline with age, Urolithin A stimulates the autophagy process, improving cellular energy metabolism and slowing down the aging process.

Anti-Aging Effects
Research suggests that Urolithin A has potential anti-aging properties, capable of slowing down cell damage and functional decline associated with aging. It enhances mitochondrial function, improving overall cellular health, especially in tissues such as muscles and the brain.

Promoting Exercise Endurance and Muscle Health
In exercise-related studies, Urolithin A has been found to enhance exercise endurance and muscle function. It helps reduce post-exercise fatigue and promotes muscle cell repair and regeneration, making it especially beneficial for the elderly or those suffering from muscle weakness.

Anti-Inflammatory Effects
Urolithin A exhibits significant anti-inflammatory effects by inhibiting inflammation-related molecules, thereby reducing chronic inflammatory responses. Chronic inflammation is linked to various metabolic diseases, such as diabetes, cardiovascular diseases, and neurodegenerative conditions. By reducing inflammation, Urolithin A helps lower the risk of these diseases.

Improving Metabolic Health
Urolithin A has also been studied for its role in improving metabolic health, particularly through its regulation of fat metabolism. It helps in weight management and has shown potential therapeutic effects in studies related to obesity and metabolic syndrome.

Safety and Side Effects

Current research indicates that Urolithin A is generally safe when used in moderation and does not exhibit significant toxic effects on the human body. However, since its metabolism is closely related to gut microbiota, its effects may vary depending on individual microbiota composition. Excessive intake may lead to discomfort, such as gastrointestinal issues or mild diarrhea. In general, the use of Urolithin A should be adjusted according to individual constitution.

Summary

Urolithin A is a natural compound derived from fruits like pomegranates, with multiple benefits, including promoting mitochondrial autophagy, anti-aging, anti-inflammatory effects, enhancing exercise endurance, and improving metabolic health. With further research into its potential, Urolithin A is considered a promising natural supplement for anti-aging and health promotion. While it is generally safe, it is recommended to use it reasonably based on individual circumstances and health conditions.