2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine CAS 90213-66-4

��发布时间：2025-02-28 ��浏览次数：530次

 Chemical Name: 2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine

CAS Number: 90213-66-4

Molecular Formula: C8H4Cl2N4

Molecular Weight: 231.05 g/mol

Appearance: Off-white to light brown powder or solid

Solubility: Soluble in organic solvents like DMSO, methanol, and dimethylformamide (DMF); poorly soluble in water

Storage Conditions: Store in a cool, dry place, away from direct sunlight, in tightly sealed containers.

What is 2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine?

2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine is an organic heterocyclic compound consisting of a pyrrole ring fused with a pyrimidine ring. It is characterized by the presence of two chlorine atoms at positions 2 and 4 on the pyrrole ring, making it a chloro-substituted heterocyclic molecule. This compound is commonly used in pharmaceutical and chemical research for developing specialized drugs and materials.

Uses and Applications

✅ Pharmaceutical Development
2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine is used as a scaffold in the synthesis of various biologically active compounds, particularly those with potential as kinase inhibitors. These inhibitors may play a role in treating cancer and other diseases.

✅ Chemical Synthesis
This compound serves as an intermediate in the synthesis of complex chemicals and drugs, especially those targeting specific enzyme systems or pathways in the body.

✅ Research in Medicinal Chemistry
Due to its structure, it is a subject of study in drug discovery, particularly in the development of compounds that can modulate the activity of enzymes involved in various cellular processes.

Safety and Precautions

Always handle this compound with proper personal protective equipment such as gloves, goggles, and lab coats.

Avoid inhalation or direct contact with skin and eyes.

Keep containers tightly sealed and store in a well-ventilated area.

Ensure proper waste disposal methods are followed, especially if working with large quantities or high concentrations.

Summary

2,4-Dichloro-7H-Pyrrolo[2,3-d]pyrimidine is a versatile compound used in pharmaceutical and chemical research. Its structural characteristics make it valuable in the development of drugs and bioactive molecules. Proper safety protocols should be followed when handling and using this compound for synthesis or research purposes.