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大类PEG4000 (Polyethylene Glycol)
CAS Number: 25322-68-3
Molecular Formula: C8H18O4
Molecular Weight: 4000 g/mol
Appearance: Colorless transparent to light yellow viscous liquid or white granules
Solubility: Soluble in water and various organic solvents
Storage Conditions: Store in a cool, dry place, avoiding high temperatures and humidity.
What is PEG4000 (Polyethylene Glycol)?
PEG4000 is a high-molecular-weight polyethylene glycol compound synthesized through the polymerization of ethylene oxide. With a molecular weight of 4000, it belongs to the higher polymerized polyethylene glycols, typically appearing as white or light yellow granules or viscous liquid. PEG4000 is commonly used in pharmaceuticals, cosmetics, and the food industry as a thickener, stabilizer, lubricant, and solvent. Since it is not absorbed by the body, it is frequently incorporated into drug delivery systems.
Functions and Applications of PEG4000
1. Drug Delivery System
PEG4000 is widely used in pharmaceuticals as a drug solvent and carrier. It enhances drug solubility, improves bioavailability, and prolongs drug release, thereby enhancing therapeutic efficacy.
2. Lubricant and Thickener
PEG4000 is a common lubricant and thickening agent in cosmetics and personal care products. It provides a smooth texture and improves the stability and application of products, frequently found in moisturizers, shampoos, and facial cleansers.
3. Industrial Applications
PEG4000 is used in industrial applications such as coatings, inks, and adhesives. As a thickener or solvent, it enhances the physical properties and stability of these products.
4. Food Industry
In the food industry, PEG4000 acts as a thickener, emulsifier, and stabilizer, improving the texture and consistency of food products. It is considered safe for consumption within regulated limits.
5. Medical Uses
PEG4000 is also applied in medical treatments, particularly for bowel cleansing and lubrication. It is commonly used as a laxative to help clear the intestines before medical procedures.
Safety and Side Effects
PEG4000 is generally recognized as safe and is widely used across various industries. For most individuals, it is non-toxic and non-irritating. However, some people may experience allergic reactions or gastrointestinal discomfort (such as diarrhea or constipation), particularly with high doses. Long-term use should follow appropriate dosage guidelines to avoid excessive intake.
Summary
PEG4000 (Polyethylene Glycol) is a high-molecular-weight compound with extensive applications in pharmaceuticals, cosmetics, the food industry, and medical treatments. It plays a crucial role in improving drug solubility, acting as a lubricant and thickener. While it has a high safety profile, proper usage guidelines should be followed to prevent potential side effects or allergic reactions.