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大类Chrysophanol 481-74-3
CAS Number: 481-74-3
Molecular Formula: C15H10O5
Molecular Weight: 270.24 g/mol
Appearance: Yellow crystalline powder
Solubility: Slightly soluble in water, easily soluble in ethanol, ether, and other organic solvents
Storage Conditions: Store in a cool, dry place, avoiding light and moisture.
What is Chrysophanol?
Chrysophanol is a naturally occurring plant compound belonging to the anthraquinone family. It is widely found in plants such as Rheum species (rhubarb) and exhibits various pharmacological activities. Chrysophanol has attracted attention for its anti-inflammatory, antioxidant, antibacterial, and anticancer properties, making it a subject of interest in medical research.
Functions and Applications of Chrysophanol
1. Anti-Inflammatory Effects
Chrysophanol has significant anti-inflammatory properties and can inhibit the production of pro-inflammatory molecules, thereby reducing inflammation. It has shown therapeutic potential, particularly in diseases related to chronic inflammation.
2. Antioxidant Properties
As a potent antioxidant, Chrysophanol scavenges free radicals and reduces oxidative damage to cells. This protective effect helps prevent oxidative stress-related cell and tissue damage, making it a potential candidate for anti-aging and age-related disease prevention.
3. Antibacterial Activity
Chrysophanol exhibits antibacterial properties and can inhibit the growth of various bacteria, including common pathogenic strains. It is often used as a natural antibacterial agent, especially in traditional herbal medicine.
4. Anticancer Potential
Studies suggest that Chrysophanol may have anticancer properties by inhibiting cancer cell proliferation and inducing apoptosis (programmed cell death) in cancer cells. This makes it a promising candidate for anticancer research.
5. Liver Protection
Chrysophanol has been found to have hepatoprotective effects by modulating antioxidant enzyme activity in the liver, reducing liver damage. It may play a beneficial role in the supportive treatment of liver diseases.
6. Digestive Health Improvement
In traditional herbal medicine, Chrysophanol is used to improve digestion and promote intestinal motility. It has mild laxative effects, making it useful as a natural aid for constipation relief.
Safety and Side Effects
While Chrysophanol has demonstrated significant pharmacological benefits, its toxicity and side effects should not be overlooked. High doses may cause gastrointestinal discomfort, diarrhea, or other adverse reactions. Long-term or high-dose use should be approached with caution, and it is recommended to consult a healthcare professional before use.
Conclusion
Chrysophanol is a natural compound with multiple pharmacological activities, widely found in rhubarb and other plants. Its anti-inflammatory, antioxidant, antibacterial, anticancer, and hepatoprotective effects make it a valuable compound in both traditional herbal medicine and modern pharmacological research. However, proper dosage control is essential to minimize potential side effects.